ملخص
Chammydial-specfic IgG and IgA antibodies were determined by a single serovar (L2) immunoperoxidase assay (IPA) in the serum of all patients that have conceived in an in vitro fertilization and embryo transfer (IVF & ET) progrom (n=106) and in a group of patients that went through the program at the same period of time and did not conceive (n=94). The prevalence rate of elevated IPA IgG (titers≥1:128) and IPA IgA (titers≥1:16) specific to chlamydiae was significantly higher (P<0.001) in the IVF&ET pregnancy loss and nonconception groups ("failures") versus the IVF&ET term pregnancy group ("successes") (74 vs 47%, odds ratio=4.1, and 34 vs 14%, odds ratio=4.3, respectively). Stepwise discriminant analysis revealed that elevated specific chlamydial IgG had the greatest effect on the variance between successes and failures in this study group. Our study indicates the possible role of past or chronic active chlamydiae infection on the "take-home baby rate" in an IVF&ET program.
اللغة الأصلية | الإنجليزيّة |
---|---|
الصفحات (من إلى) | 222-227 |
عدد الصفحات | 6 |
دورية | Journal of in Vitro Fertilization and Embryo Transfer |
مستوى الصوت | 6 |
رقم الإصدار | 4 |
المعرِّفات الرقمية للأشياء | |
حالة النشر | نُشِر - أغسطس 1989 |
منشور خارجيًا | نعم |