T cell derived IgE binding factors inhibit IgE-specific rosettes on basophilic leukaemic cells and lymphocytes

M. A. Firer, Z. Eshhar

نتاج البحث: نشر في مجلةمقالةمراجعة النظراء

ملخص

T cell derived IgE-binding factors inhibited the formation of IgE-specific rosettes on both rat basophilic leukaemic cells and lymphocytes. This was demonstrated by IgE-binding factors released from either IgE-pulsed T cells or adherent cells as well as from IgE-binding factor producing hybridomas. The different binding factors inhibited the IgE-rosettes to a different degree when tested on basophils and lymphocytes, most likely due to the higher affinity for IgE of the former cell type. The results indicate that rat basophils and mouse T cells may recognize common epitopes on the Fc portion of IgE.

اللغة الأصليةالإنجليزيّة
الصفحات (من إلى)1-5
عدد الصفحات5
دوريةImmunology Letters
مستوى الصوت13
رقم الإصدار1-2
المعرِّفات الرقمية للأشياء
حالة النشرنُشِر - أغسطس 1986
منشور خارجيًانعم

بصمة

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