Persistence and complex evolution of fluoroquinolone-resistant Streptococcus pneumoniae Clone

Debby Ben-David; Mitchell J. Schwaber; Amos Adler; Samira Masarwa; Rotem Edgar; Shiri Navon-Venezia; David Schwartz; Nurith Porat; Tali Kotlovsky; Nikolay Polivkin; Irina Weinberg; Avraham Lazary; Nissim Ohana; Ron Dagan

doi:10.3201/eid2005.130142

Persistence and complex evolution of fluoroquinolone-resistant Streptococcus pneumoniae Clone

Debby Ben-David
, Mitchell J. Schwaber
, Amos Adler
, Samira Masarwa
, Rotem Edgar
, Shiri Navon-Venezia
, David Schwartz
, Nurith Porat
, Tali Kotlovsky
, Nikolay Polivkin
, Irina Weinberg
, Avraham Lazary
, Nissim Ohana
, Ron Dagan

نتاج البحث: نشر في مجلة › مقالة › مراجعة النظراء

11 اقتباسات (Scopus)

ملخص

Prolonged outbreaks of multidrug-resistant Streptococcus pneumoniae in health care facilities are uncommon. We found persistent transmission of a fluroquinolone-resistant S. pneumoniae clone during 2006-2011 in a post-acute care facility in Israel, despite mandatory vaccination and fluoroquinolone restriction. Capsular switch and multiple antimicrobial nonsusceptibility mutations occurred within this single clone. The persistent transmission of fluoroquinolone- resistant S. pneumoniae during a 5-year period underscores the importance of long-term care facilities as potential reservoirs of multidrug-resistant streptococci.

اللغة الأصلية	الإنجليزيّة
الصفحات (من إلى)	799-805
عدد الصفحات	7
دورية	Emerging Infectious Diseases
مستوى الصوت	20
رقم الإصدار	5
المعرِّفات الرقمية للأشياء	https://doi.org/10.3201/eid2005.130142
حالة النشر	نُشِر - مايو 2014
منشور خارجيًا	نعم

الوصول إلى المستند

10.3201/eid2005.130142

الملفات والروابط الأخرى

Link to publication in Scopus

قم بذكر هذا

Ben-David, D., Schwaber, M. J., Adler, A., Masarwa, S., Edgar, R., Navon-Venezia, S., Schwartz, D., Porat, N., Kotlovsky, T., Polivkin, N., Weinberg, I., Lazary, A., Ohana, N., & Dagan, R. (2014). Persistence and complex evolution of fluoroquinolone-resistant Streptococcus pneumoniae Clone. Emerging Infectious Diseases, 20(5), 799-805. https://doi.org/10.3201/eid2005.130142

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title = "Persistence and complex evolution of fluoroquinolone-resistant Streptococcus pneumoniae Clone",

abstract = "Prolonged outbreaks of multidrug-resistant Streptococcus pneumoniae in health care facilities are uncommon. We found persistent transmission of a fluroquinolone-resistant S. pneumoniae clone during 2006-2011 in a post-acute care facility in Israel, despite mandatory vaccination and fluoroquinolone restriction. Capsular switch and multiple antimicrobial nonsusceptibility mutations occurred within this single clone. The persistent transmission of fluoroquinolone- resistant S. pneumoniae during a 5-year period underscores the importance of long-term care facilities as potential reservoirs of multidrug-resistant streptococci.",

author = "Debby Ben-David and Schwaber, \{Mitchell J.\} and Amos Adler and Samira Masarwa and Rotem Edgar and Shiri Navon-Venezia and David Schwartz and Nurith Porat and Tali Kotlovsky and Nikolay Polivkin and Irina Weinberg and Avraham Lazary and Nissim Ohana and Ron Dagan",

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doi = "10.3201/eid2005.130142",

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Ben-David, D, Schwaber, MJ, Adler, A, Masarwa, S, Edgar, R, Navon-Venezia, S, Schwartz, D, Porat, N, Kotlovsky, T, Polivkin, N, Weinberg, I, Lazary, A, Ohana, N & Dagan, R 2014, 'Persistence and complex evolution of fluoroquinolone-resistant Streptococcus pneumoniae Clone', Emerging Infectious Diseases, المجلد 20, رقم 5, الصفحات 799-805. https://doi.org/10.3201/eid2005.130142

TY - JOUR

T1 - Persistence and complex evolution of fluoroquinolone-resistant Streptococcus pneumoniae Clone

AU - Ben-David, Debby

AU - Schwaber, Mitchell J.

AU - Adler, Amos

AU - Masarwa, Samira

AU - Edgar, Rotem

AU - Navon-Venezia, Shiri

AU - Schwartz, David

AU - Porat, Nurith

AU - Kotlovsky, Tali

AU - Polivkin, Nikolay

AU - Weinberg, Irina

AU - Lazary, Avraham

AU - Ohana, Nissim

AU - Dagan, Ron

PY - 2014/5

Y1 - 2014/5

N2 - Prolonged outbreaks of multidrug-resistant Streptococcus pneumoniae in health care facilities are uncommon. We found persistent transmission of a fluroquinolone-resistant S. pneumoniae clone during 2006-2011 in a post-acute care facility in Israel, despite mandatory vaccination and fluoroquinolone restriction. Capsular switch and multiple antimicrobial nonsusceptibility mutations occurred within this single clone. The persistent transmission of fluoroquinolone- resistant S. pneumoniae during a 5-year period underscores the importance of long-term care facilities as potential reservoirs of multidrug-resistant streptococci.

AB - Prolonged outbreaks of multidrug-resistant Streptococcus pneumoniae in health care facilities are uncommon. We found persistent transmission of a fluroquinolone-resistant S. pneumoniae clone during 2006-2011 in a post-acute care facility in Israel, despite mandatory vaccination and fluoroquinolone restriction. Capsular switch and multiple antimicrobial nonsusceptibility mutations occurred within this single clone. The persistent transmission of fluoroquinolone- resistant S. pneumoniae during a 5-year period underscores the importance of long-term care facilities as potential reservoirs of multidrug-resistant streptococci.

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U2 - 10.3201/eid2005.130142

DO - 10.3201/eid2005.130142

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C2 - 24751142

AN - SCOPUS:84898838025

SN - 1080-6040

VL - 20

SP - 799

EP - 805

JO - Emerging Infectious Diseases

JF - Emerging Infectious Diseases

IS - 5

ER -

Persistence and complex evolution of fluoroquinolone-resistant Streptococcus pneumoniae Clone

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الملفات والروابط الأخرى

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