Pamidronate-induced nephrotoxic tubular necrosis - A case report

S. Smetana, A. Michlin, E. Rosenman, A. Biro, M. Boaz, Z. Katzir

نتاج البحث: نشر في مجلةمقالةمراجعة النظراء

37 اقتباسات (Scopus)

ملخص

Few cases of pamidronate (bis-phosphonate class of drugs) nephrotoxicity in humans have been previously reported in the literature. In 7 patients, the pamidronate-related nephrotoxicity was attributed to focal collapsing glomerulosclerosis [Markowitz et al. 2001], and in 1 patient was related to tubulo-interstitial inflammatory nephritis [Van Doorn et al. 2001]. We report herein on a 65-year-old Caucasian female patient who presented with acute chronic renal failure due to pamidronate-induced toxic proximal tubular necrosis without immunologic or inflammatory tubulo-interstitial involvement. The acute pattern of renal failure resolved following cessation of pamidronate administration in this patient for osteoporosis; the patient also had a monoclonal gammopathy of unspecific origin (MGUS).

اللغة الأصليةالإنجليزيّة
الصفحات (من إلى)63-67
عدد الصفحات5
دوريةClinical Nephrology
مستوى الصوت61
رقم الإصدار1
المعرِّفات الرقمية للأشياء
حالة النشرنُشِر - يناير 2004
منشور خارجيًانعم

بصمة

أدرس بدقة موضوعات البحث “Pamidronate-induced nephrotoxic tubular necrosis - A case report'. فهما يشكلان معًا بصمة فريدة.

قم بذكر هذا