Hypervigilance or shutdown? Electrophysiological processing of trauma-unrelated aversive stimuli after traumatic life events

نتاج البحث: نشر في مجلةمقالةمراجعة النظراء

1 اقتباس (Scopus)

ملخص

Post-Traumatic Stress Disorder (PTSD) research indicates that hyper-reactivity to trauma-related stimuli reflects reduced prefrontal cortex (PFC) modulation of amygdala reactivity. However, other studies indicate a dissociative “shutdown” reaction to overwhelming aversive stimuli, possibly reflecting PFC over-modulation. To explore this, we used an Event-Related Potential (ERP) oddball paradigm to study P3 responses in the presence of the following: 1. Trauma-unrelated morbid distractors (e.g., “injured bear”) related to the Rorschach inkblot test, and 2. Negative distractors (e.g., “significant failure”), among participants with high post-traumatic stress symptoms (PTS; n = 20), low PTS (n = 17), and controls (n = 15). Distractors were presented at 20% frequency amongst the more frequent (60%) neutral standard stimuli (e.g., “desk lamp”) and the equally frequent (20%) neutral trauma-unrelated target stimulus (“golden fish”). P3 amplitudes were high in the presence of morbid distractors and low in the presence of negative distractors only amongst the control group. Possible mechanisms underlying the lack of P3 amplitude modulation after trauma are discussed.

اللغة الأصليةالإنجليزيّة
الصفحات (من إلى)1185-1197
عدد الصفحات13
دوريةExperimental Brain Research
مستوى الصوت241
رقم الإصدار4
المعرِّفات الرقمية للأشياء
حالة النشرنُشِر - أبريل 2023

بصمة

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