Heat-shock transcription factor HSF1 has a critical role in human epidermal growth factor receptor-2-induced cellular transformation and tumorigenesis

Biochemistry, Genetics and Molecular Biology

• Carcinogenesis 100%
• Epidermal Growth Factor Receptor 100%
• HSF1 100%
• Cell Transformation 100%
• Heat Shock Factor 100%
• P21 44%
• Survivin 44%
• Downregulation 22%
• Heat Shock Protein 11%
• Upregulation 11%
• Heat Shock Response 11%
• Growth Inhibition 11%
• P53 11%
• Tumor Progression 11%
• Molecular Weight 11%
• Cyclin-Dependent Kinase 11%
• Oncogene 11%
• Hsp27 11%
• Nude Mouse 11%

Keyphrases

• Human Epidermal Growth Factor Receptor 2 (HER2) 100%
• Tumorigenesis 100%
• Cell Transformation 100%
• Heat Shock Factor 1 (HSF1) 100%
• Knockdown 36%
• Survivin 36%
• Senescence 18%
• MCF10A Cells 18%
• Growth Arrest 18%
• Oncogene 9%
• Neoplastic Transformation 9%
• Tumor Growth 9%
• Overexpression 9%
• Tumor 9%
• Heat Shock Response 9%
• Growth Inhibition 9%
• Cancer Cell Lines 9%
• Tumor-associated 9%
• Focus Formation 9%
• Cell Senescence 9%
• Xenograft 9%
• Heat Shock Protein 27 (HSP27) 9%
• Small Molecular Weight Inhibitors 9%
• Nude Mice Xenograft 9%
• Heat Shock Protein 72 9%
• Human-to-human 9%
• Mitotic Regulator 9%
• Breast Tumor 9%
• Human Epidermal Growth Factor Receptor 2-positive Breast Cancer 9%
• Mammary Epithelial 9%
• Cyclin-dependent Kinase Inhibitor p21 9%

Pharmacology, Toxicology and Pharmaceutical Science

• Carcinogenesis 100%
• Heat Shock Transcription Factor 100%
• Epidermal Growth Factor Receptor 2 100%
• Gamma Urogastrone 100%
• Survivin 57%
• Neoplasm 28%
• Growth Disorder 28%
• Tumor Growth 14%
• Protein P53 14%
• Cyclin Dependent Kinase Inhibitor 1A 14%
• Human Epidermal Growth Factor Receptor 2 Positive Breast Cancer 14%
• Heat Shock Protein 72 14%
• Nude Mouse 14%
• Breast Tumor 14%