Genetics of bone mineral density: Evidence for a major pleiotropic effect from an intercontinental study

Keyphrases

• Genetic Effects 100%
• Pleiotropic Effects 100%
• Bone Mineral Density 100%
• Genetic Factors 80%
• Skeletal Site 80%
• Environmental Impact 40%
• Major Locus 40%
• Genetic Structure 40%
• Covariation 40%
• Osteoporotic Fractures 40%
• Lumbar Spine 40%
• Residual Correlation 40%
• Femoral Neck BMD 40%
• Genetic Correlation 20%
• Europe 20%
• Trabecular Bone 20%
• North America 20%
• Bivariate 20%
• Major Gene 20%
• Pedigree 20%
• Gene Effects 20%
• Environmental Transmission 20%
• Parameter Estimation 20%
• Complex Segregation Analysis 20%
• Inter-individual Variation 20%
• Osteoporosis 20%
• Fracture Risk 20%
• Genetic Studies 20%
• Genetic Loci 20%
• Australia 20%
• Genetic Determination 20%
• Heterogeneous Samples 20%
• Parsimonious Models 20%
• Genetic Transmission 20%
• Pathogenic Process 20%
• Liability Process 20%
• Close Linkage 20%
• Phenotypic Covariation 20%
• Hand Phalanges 20%

Biochemistry, Genetics and Molecular Biology

• Genetic Determinism 100%
• Pleiotropy 100%
• Genetics 100%
• Bone Density 100%
• Gene Linkage 25%
• Genetic Structure 25%
• Genetic Correlation 12%
• Pedigree 12%
• Major Gene 12%
• Complex Segregation Analysis 12%
• Gene Locus 12%