TY - JOUR
T1 - Fluorescence-based detection of benzene, toluene, ethylbenzene, xylene, and cumene (BTEXC) compounds in fuel-contaminated snow environments
AU - DiScenza, Dana J.
AU - Intravaia, Lauren E.
AU - Healy, Anna
AU - Dubrawski, Sage B.
AU - Levine, Mindy
N1 - Publisher Copyright:
© 2019 by the authors.
PY - 2019
Y1 - 2019
N2 - Reported herein is the sensitive and selective cyclodextrin-promoted fluorescence detection of benzene, toluene, ethylbenzene, xylene, and cumene (BTEXC) fuel components in contaminated snow samples collected from several locations in the state of Rhode Island. This detection method uses cyclodextrin as a supramolecular scaffold to promote analyte-specific, proximity-induced fluorescence modulation of a high-quantum-yield fluorophore, which leads to unique fluorescence responses for each cyclodextrin-analyte-fluorophore combination investigated and enables unique pattern identifiers for each analyte using linear discriminant analysis (LDA). This detection method operates with high levels of sensitivity (sub-micromolar detection limits), selectivity (100% differentiation between structurally similar compounds, such as ortho-, meta-, and para-xylene isomers), and broad applicability (for different snow samples with varying chemical composition, pH, and electrical conductivity). The high selectivity, sensitivity, and broad applicability of this method indicate significant potential in the development of practical detection devices for aromatic toxicants in complex environments.
AB - Reported herein is the sensitive and selective cyclodextrin-promoted fluorescence detection of benzene, toluene, ethylbenzene, xylene, and cumene (BTEXC) fuel components in contaminated snow samples collected from several locations in the state of Rhode Island. This detection method uses cyclodextrin as a supramolecular scaffold to promote analyte-specific, proximity-induced fluorescence modulation of a high-quantum-yield fluorophore, which leads to unique fluorescence responses for each cyclodextrin-analyte-fluorophore combination investigated and enables unique pattern identifiers for each analyte using linear discriminant analysis (LDA). This detection method operates with high levels of sensitivity (sub-micromolar detection limits), selectivity (100% differentiation between structurally similar compounds, such as ortho-, meta-, and para-xylene isomers), and broad applicability (for different snow samples with varying chemical composition, pH, and electrical conductivity). The high selectivity, sensitivity, and broad applicability of this method indicate significant potential in the development of practical detection devices for aromatic toxicants in complex environments.
KW - BTEXC
KW - Cyclodextrin
KW - Fluorescence spectroscopy
KW - Snow
UR - http://www.scopus.com/inward/record.url?scp=85067086148&partnerID=8YFLogxK
U2 - 10.3390/CHEMOSENSORS7010005
DO - 10.3390/CHEMOSENSORS7010005
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AN - SCOPUS:85067086148
SN - 2227-9040
VL - 7
JO - Chemosensors
JF - Chemosensors
IS - 1
M1 - 5
ER -