First report of a persistent oropharyngeal infection of type 2 vaccine-derived poliovirus (iVDPV2) in a primary immune deficient (PID) patient after eradication of wild type 2 poliovirus

Merav Weil; Galia Rahav; Raz Somech; Tali Stauber; Jacqueline Alfandari; Leah Weiss; Ilana Silberstein; Victoria Indenbaum; Itay Bar Or; Ella Mendelson; Danit Sofer; Lester M. Shulman

doi:10.1016/j.ijid.2019.03.037

First report of a persistent oropharyngeal infection of type 2 vaccine-derived poliovirus (iVDPV2) in a primary immune deficient (PID) patient after eradication of wild type 2 poliovirus

Merav Weil
, Galia Rahav
, Raz Somech
, Tali Stauber
, Jacqueline Alfandari
, Leah Weiss
, Ilana Silberstein
, Victoria Indenbaum
, Itay Bar Or
, Ella Mendelson
, Danit Sofer
, Lester M. Shulman

نتاج البحث: نشر في مجلة › مقالة › مراجعة النظراء

5 اقتباسات (Scopus)

ملخص

This is the first report of persistent oropharyngeal mucosal infection with type 2 poliovirus (iVDPV2) in a primary immune deficient patient (PID) after wild type 2 poliovirus eradication. The iVDPV2 also established persistence in the gut. iVDPV2 at both loci evolved independently. Persistent oral infections present a potential risk for oral-oral as well as fecal-oral poliovirus transmission during transition to a poliovirus 2-free world.

اللغة الأصلية	الإنجليزيّة
الصفحات (من إلى)	40-43
عدد الصفحات	4
دورية	International Journal of Infectious Diseases
مستوى الصوت	83
المعرِّفات الرقمية للأشياء	https://doi.org/10.1016/j.ijid.2019.03.037
حالة النشر	نُشِر - يونيو 2019
منشور خارجيًا	نعم

الوصول إلى المستند

10.1016/j.ijid.2019.03.037

الملفات والروابط الأخرى

Link to publication in Scopus

بصمة

أدرس بدقة موضوعات البحث “First report of a persistent oropharyngeal infection of type 2 vaccine-derived poliovirus (iVDPV2) in a primary immune deficient (PID) patient after eradication of wild type 2 poliovirus'. فهما يشكلان معًا بصمة فريدة.

قم بذكر هذا

Weil, M., Rahav, G., Somech, R., Stauber, T., Alfandari, J., Weiss, L., Silberstein, I., Indenbaum, V., Or, I. B., Mendelson, E., Sofer, D., & Shulman, L. M. (2019). First report of a persistent oropharyngeal infection of type 2 vaccine-derived poliovirus (iVDPV2) in a primary immune deficient (PID) patient after eradication of wild type 2 poliovirus. International Journal of Infectious Diseases, 83, 40-43. https://doi.org/10.1016/j.ijid.2019.03.037

@article{cd6e9217e33d40a68e5e7591e5a68914,

title = "First report of a persistent oropharyngeal infection of type 2 vaccine-derived poliovirus (iVDPV2) in a primary immune deficient (PID) patient after eradication of wild type 2 poliovirus",

abstract = "This is the first report of persistent oropharyngeal mucosal infection with type 2 poliovirus (iVDPV2) in a primary immune deficient patient (PID) after wild type 2 poliovirus eradication. The iVDPV2 also established persistence in the gut. iVDPV2 at both loci evolved independently. Persistent oral infections present a potential risk for oral-oral as well as fecal-oral poliovirus transmission during transition to a poliovirus 2-free world.",

keywords = "Contact isolation, Droplet isolation, Oropharyngeal mucosa, Primary immune deficiency (PID), Stools, Type 2 vaccine-derived poliovirus (iVDPV2)",

author = "Merav Weil and Galia Rahav and Raz Somech and Tali Stauber and Jacqueline Alfandari and Leah Weiss and Ilana Silberstein and Victoria Indenbaum and Or, \{Itay Bar\} and Ella Mendelson and Danit Sofer and Shulman, \{Lester M.\}",

note = "Publisher Copyright: {\textcopyright} 2019 The Authors",

year = "2019",

month = jun,

doi = "10.1016/j.ijid.2019.03.037",

language = "אנגלית",

volume = "83",

pages = "40--43",

journal = "International Journal of Infectious Diseases",

issn = "1201-9712",

publisher = "Elsevier B.V.",

}

Weil, M, Rahav, G, Somech, R, Stauber, T, Alfandari, J, Weiss, L, Silberstein, I, Indenbaum, V, Or, IB, Mendelson, E, Sofer, D & Shulman, LM 2019, 'First report of a persistent oropharyngeal infection of type 2 vaccine-derived poliovirus (iVDPV2) in a primary immune deficient (PID) patient after eradication of wild type 2 poliovirus', International Journal of Infectious Diseases, المجلد 83, الصفحات 40-43. https://doi.org/10.1016/j.ijid.2019.03.037

First report of a persistent oropharyngeal infection of type 2 vaccine-derived poliovirus (iVDPV2) in a primary immune deficient (PID) patient after eradication of wild type 2 poliovirus. / Weil, Merav; Rahav, Galia; Somech, Raz وآخرون.
في: International Journal of Infectious Diseases, المجلد 83, ٠٦.٢٠١٩, صفحة 40-43.

نتاج البحث: نشر في مجلة › مقالة › مراجعة النظراء

TY - JOUR

T1 - First report of a persistent oropharyngeal infection of type 2 vaccine-derived poliovirus (iVDPV2) in a primary immune deficient (PID) patient after eradication of wild type 2 poliovirus

AU - Weil, Merav

AU - Rahav, Galia

AU - Somech, Raz

AU - Stauber, Tali

AU - Alfandari, Jacqueline

AU - Weiss, Leah

AU - Silberstein, Ilana

AU - Indenbaum, Victoria

AU - Or, Itay Bar

AU - Mendelson, Ella

AU - Sofer, Danit

AU - Shulman, Lester M.

PY - 2019/6

Y1 - 2019/6

N2 - This is the first report of persistent oropharyngeal mucosal infection with type 2 poliovirus (iVDPV2) in a primary immune deficient patient (PID) after wild type 2 poliovirus eradication. The iVDPV2 also established persistence in the gut. iVDPV2 at both loci evolved independently. Persistent oral infections present a potential risk for oral-oral as well as fecal-oral poliovirus transmission during transition to a poliovirus 2-free world.

AB - This is the first report of persistent oropharyngeal mucosal infection with type 2 poliovirus (iVDPV2) in a primary immune deficient patient (PID) after wild type 2 poliovirus eradication. The iVDPV2 also established persistence in the gut. iVDPV2 at both loci evolved independently. Persistent oral infections present a potential risk for oral-oral as well as fecal-oral poliovirus transmission during transition to a poliovirus 2-free world.

KW - Contact isolation

KW - Droplet isolation

KW - Oropharyngeal mucosa

KW - Primary immune deficiency (PID)

KW - Stools

KW - Type 2 vaccine-derived poliovirus (iVDPV2)

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AN - SCOPUS:85064887789

SN - 1201-9712

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JO - International Journal of Infectious Diseases

JF - International Journal of Infectious Diseases

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