Excision of nucleoside analogs from DNA by p53 protein, a potential cellular mechanism of resistance to inhibitors of human immunodeficiency virus type 1 reverse transcriptase

Mary Bakhanashvili; Elena Novitsky; Ethan Rubinstein; Itzchak Levy; Galia Rahav

doi:10.1128/AAC.49.4.1576-1579.2005

Excision of nucleoside analogs from DNA by p53 protein, a potential cellular mechanism of resistance to inhibitors of human immunodeficiency virus type 1 reverse transcriptase

Mary Bakhanashvili
, Elena Novitsky
, Ethan Rubinstein
, Itzchak Levy
, Galia Rahav

نتاج البحث: نشر في مجلة › مقالة › مراجعة النظراء

7 اقتباسات (Scopus)

ملخص

We investigated the ability of p53 in cytoplasm to excise nucleoside analogs (NAs). A decrease in incorporation of NAs by human immunodeficiency virus type 1 reverse transcriptase and their excision from DNA by p53, provided by the cytoplasmic fraction of LCC2 cells, suggest that p53 in cytoplasm may act as an external proofreader for NA incorporation.

اللغة الأصلية	الإنجليزيّة
الصفحات (من إلى)	1576-1579
عدد الصفحات	4
دورية	Antimicrobial Agents and Chemotherapy
مستوى الصوت	49
رقم الإصدار	4
المعرِّفات الرقمية للأشياء	https://doi.org/10.1128/AAC.49.4.1576-1579.2005
حالة النشر	نُشِر - أبريل 2005
منشور خارجيًا	نعم

الوصول إلى المستند

10.1128/AAC.49.4.1576-1579.2005

الملفات والروابط الأخرى

Link to publication in Scopus

قم بذكر هذا

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title = "Excision of nucleoside analogs from DNA by p53 protein, a potential cellular mechanism of resistance to inhibitors of human immunodeficiency virus type 1 reverse transcriptase",

abstract = "We investigated the ability of p53 in cytoplasm to excise nucleoside analogs (NAs). A decrease in incorporation of NAs by human immunodeficiency virus type 1 reverse transcriptase and their excision from DNA by p53, provided by the cytoplasmic fraction of LCC2 cells, suggest that p53 in cytoplasm may act as an external proofreader for NA incorporation.",

author = "Mary Bakhanashvili and Elena Novitsky and Ethan Rubinstein and Itzchak Levy and Galia Rahav",

year = "2005",

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doi = "10.1128/AAC.49.4.1576-1579.2005",

language = "אנגלית",

volume = "49",

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journal = "Antimicrobial Agents and Chemotherapy",

issn = "0066-4804",

publisher = "American Society for Microbiology",

number = "4",

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Bakhanashvili, M, Novitsky, E, Rubinstein, E, Levy, I & Rahav, G 2005, 'Excision of nucleoside analogs from DNA by p53 protein, a potential cellular mechanism of resistance to inhibitors of human immunodeficiency virus type 1 reverse transcriptase', Antimicrobial Agents and Chemotherapy, المجلد 49, رقم 4, الصفحات 1576-1579. https://doi.org/10.1128/AAC.49.4.1576-1579.2005

Excision of nucleoside analogs from DNA by p53 protein, a potential cellular mechanism of resistance to inhibitors of human immunodeficiency virus type 1 reverse transcriptase. / Bakhanashvili, Mary; Novitsky, Elena; Rubinstein, Ethan وآخرون.
في: Antimicrobial Agents and Chemotherapy, المجلد 49, رقم 4, 04.2005, صفحة 1576-1579.

نتاج البحث: نشر في مجلة › مقالة › مراجعة النظراء

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T1 - Excision of nucleoside analogs from DNA by p53 protein, a potential cellular mechanism of resistance to inhibitors of human immunodeficiency virus type 1 reverse transcriptase

AU - Bakhanashvili, Mary

AU - Novitsky, Elena

AU - Rubinstein, Ethan

AU - Levy, Itzchak

AU - Rahav, Galia

PY - 2005/4

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N2 - We investigated the ability of p53 in cytoplasm to excise nucleoside analogs (NAs). A decrease in incorporation of NAs by human immunodeficiency virus type 1 reverse transcriptase and their excision from DNA by p53, provided by the cytoplasmic fraction of LCC2 cells, suggest that p53 in cytoplasm may act as an external proofreader for NA incorporation.

AB - We investigated the ability of p53 in cytoplasm to excise nucleoside analogs (NAs). A decrease in incorporation of NAs by human immunodeficiency virus type 1 reverse transcriptase and their excision from DNA by p53, provided by the cytoplasmic fraction of LCC2 cells, suggest that p53 in cytoplasm may act as an external proofreader for NA incorporation.

UR - https://www.scopus.com/pages/publications/16244423293

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C2 - 15793143

AN - SCOPUS:16244423293

SN - 0066-4804

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JO - Antimicrobial Agents and Chemotherapy

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IS - 4

ER -

Excision of nucleoside analogs from DNA by p53 protein, a potential cellular mechanism of resistance to inhibitors of human immunodeficiency virus type 1 reverse transcriptase

ملخص

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الملفات والروابط الأخرى

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