Decline in immunity to polio among young adults

Itamar Grotto; Rachel Handsher; Michael Gdalevich; Daniel Mimouni; Michael Huerta; Manfred S. Green; Ella Mendelson; Ofer Shpilberg

doi:10.1016/S0264-410X(01)00165-7

Decline in immunity to polio among young adults

Itamar Grotto
, Rachel Handsher
, Michael Gdalevich
, Daniel Mimouni
, Michael Huerta
, Manfred S. Green
, Ella Mendelson
, Ofer Shpilberg

نتاج البحث: نشر في مجلة › مقالة › مراجعة النظراء

19 اقتباسات (Scopus)

ملخص

A serologic survey was conducted on a population-based representative sample of 521 18-year-old soldiers recruited to the Israel Defence Forces in 1997. The prevalence of neutralizing antibodies and geometric mean titers (GMTs) against the three types of poliovirus (Mahoney, MEF and Saukett strains) were found to be 98.7% (GMT - 169.95), 99.6% (GMT - 297.14) and 96.4% (GMT - 59.48), respectively. These GMTs are markedly lower than those recorded 4 years after booster vaccination carried out during a 1988 polio outbreak, and suggest a decline in immunity against polio among young adults. These findings support the policy of routine revaccination of children and adolescents in countries at risk of imported polioviruses and of revaccination of adults traveling to areas to which polio is endemic.

اللغة الأصلية	الإنجليزيّة
الصفحات (من إلى)	4162-4166
عدد الصفحات	5
دورية	Vaccine
مستوى الصوت	19
رقم الإصدار	30
المعرِّفات الرقمية للأشياء	https://doi.org/10.1016/S0264-410X(01)00165-7
حالة النشر	نُشِر - 20 يوليو 2001
منشور خارجيًا	نعم

الوصول إلى المستند

10.1016/S0264-410X(01)00165-7

الملفات والروابط الأخرى

Link to publication in Scopus

قم بذكر هذا

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title = "Decline in immunity to polio among young adults",

abstract = "A serologic survey was conducted on a population-based representative sample of 521 18-year-old soldiers recruited to the Israel Defence Forces in 1997. The prevalence of neutralizing antibodies and geometric mean titers (GMTs) against the three types of poliovirus (Mahoney, MEF and Saukett strains) were found to be 98.7\% (GMT - 169.95), 99.6\% (GMT - 297.14) and 96.4\% (GMT - 59.48), respectively. These GMTs are markedly lower than those recorded 4 years after booster vaccination carried out during a 1988 polio outbreak, and suggest a decline in immunity against polio among young adults. These findings support the policy of routine revaccination of children and adolescents in countries at risk of imported polioviruses and of revaccination of adults traveling to areas to which polio is endemic.",

keywords = "Antibodies, Immunity, Poliovaccine",

author = "Itamar Grotto and Rachel Handsher and Michael Gdalevich and Daniel Mimouni and Michael Huerta and Green, \{Manfred S.\} and Ella Mendelson and Ofer Shpilberg",

year = "2001",

month = jul,

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doi = "10.1016/S0264-410X(01)00165-7",

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TY - JOUR

T1 - Decline in immunity to polio among young adults

AU - Grotto, Itamar

AU - Handsher, Rachel

AU - Gdalevich, Michael

AU - Mimouni, Daniel

AU - Huerta, Michael

AU - Green, Manfred S.

AU - Mendelson, Ella

AU - Shpilberg, Ofer

PY - 2001/7/20

Y1 - 2001/7/20

N2 - A serologic survey was conducted on a population-based representative sample of 521 18-year-old soldiers recruited to the Israel Defence Forces in 1997. The prevalence of neutralizing antibodies and geometric mean titers (GMTs) against the three types of poliovirus (Mahoney, MEF and Saukett strains) were found to be 98.7% (GMT - 169.95), 99.6% (GMT - 297.14) and 96.4% (GMT - 59.48), respectively. These GMTs are markedly lower than those recorded 4 years after booster vaccination carried out during a 1988 polio outbreak, and suggest a decline in immunity against polio among young adults. These findings support the policy of routine revaccination of children and adolescents in countries at risk of imported polioviruses and of revaccination of adults traveling to areas to which polio is endemic.

AB - A serologic survey was conducted on a population-based representative sample of 521 18-year-old soldiers recruited to the Israel Defence Forces in 1997. The prevalence of neutralizing antibodies and geometric mean titers (GMTs) against the three types of poliovirus (Mahoney, MEF and Saukett strains) were found to be 98.7% (GMT - 169.95), 99.6% (GMT - 297.14) and 96.4% (GMT - 59.48), respectively. These GMTs are markedly lower than those recorded 4 years after booster vaccination carried out during a 1988 polio outbreak, and suggest a decline in immunity against polio among young adults. These findings support the policy of routine revaccination of children and adolescents in countries at risk of imported polioviruses and of revaccination of adults traveling to areas to which polio is endemic.

KW - Antibodies

KW - Immunity

KW - Poliovaccine

UR - https://www.scopus.com/pages/publications/0035919539

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C2 - 11457541

AN - SCOPUS:0035919539

SN - 0264-410X

VL - 19

SP - 4162

EP - 4166

JO - Vaccine

JF - Vaccine

IS - 30

ER -

Decline in immunity to polio among young adults

ملخص

الوصول إلى المستند

الملفات والروابط الأخرى

بصمة

قم بذكر هذا