TY - JOUR
T1 - Colorimetric Detection of Aliphatic Alcohols in β-Cyclodextrin Solutions
AU - Haynes, Anna
AU - Halpert, Priva
AU - Levine, Mindy
N1 - Publisher Copyright:
© 2019 American Chemical Society.
PY - 2019/11/5
Y1 - 2019/11/5
N2 - The sensitive, selective, and practical detection of aliphatic alcohols is a continuing technical challenge with significant impact in public health research and environmental remediation efforts. Reported herein is the use of a β-cyclodextrin derivative to promote proximity-induced interactions between aliphatic alcohol analytes and a brightly colored organic dye, which resulted in highly analyte-specific color changes that enabled accurate alcohol identification. Linear discriminant analysis of the color changes enabled 100% differentiation of the colorimetric signals obtained from methanol, ethanol, and isopropanol in combination with BODIPY and Rhodamine dyes. The resulting solution-state detection system has significant broad-based applicability because it uses only easily available materials to achieve such detection with moderate limits of detection obtained. Future research with this sensor system will focus on decreasing limits of detection as well as on optimizing the system for quantitative detection applications.
AB - The sensitive, selective, and practical detection of aliphatic alcohols is a continuing technical challenge with significant impact in public health research and environmental remediation efforts. Reported herein is the use of a β-cyclodextrin derivative to promote proximity-induced interactions between aliphatic alcohol analytes and a brightly colored organic dye, which resulted in highly analyte-specific color changes that enabled accurate alcohol identification. Linear discriminant analysis of the color changes enabled 100% differentiation of the colorimetric signals obtained from methanol, ethanol, and isopropanol in combination with BODIPY and Rhodamine dyes. The resulting solution-state detection system has significant broad-based applicability because it uses only easily available materials to achieve such detection with moderate limits of detection obtained. Future research with this sensor system will focus on decreasing limits of detection as well as on optimizing the system for quantitative detection applications.
UR - http://www.scopus.com/inward/record.url?scp=85074497556&partnerID=8YFLogxK
U2 - 10.1021/acsomega.9b02612
DO - 10.1021/acsomega.9b02612
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AN - SCOPUS:85074497556
SN - 2470-1343
VL - 4
SP - 18361
EP - 18369
JO - ACS Omega
JF - ACS Omega
IS - 19
ER -