TY - JOUR
T1 - Bright fluorogenic squaraines with tuned cell entry for selective imaging of plasma membrane vs. endoplasmic reticulum
AU - Collot, Mayeul
AU - Kreder, Rémy
AU - Tatarets, Anatoliy L.
AU - Patsenker, Leonid D.
AU - Mely, Yves
AU - Klymchenko, Andrey S.
N1 - Publisher Copyright:
© 2015 The Royal Society of Chemistry.
PY - 2015
Y1 - 2015
N2 - A rational design of squaraine dyes with lipophilic and zwitterionic groups tunes cell entry, allowing for selective far-red/near-infrared imaging of plasma membrane vs. endoplasmic reticulum. They exhibit up to 110-fold fluorescence enhancement in biomembranes and enable cellular imaging at 1 nM concentration, which make them the brightest membrane probes to date.
AB - A rational design of squaraine dyes with lipophilic and zwitterionic groups tunes cell entry, allowing for selective far-red/near-infrared imaging of plasma membrane vs. endoplasmic reticulum. They exhibit up to 110-fold fluorescence enhancement in biomembranes and enable cellular imaging at 1 nM concentration, which make them the brightest membrane probes to date.
UR - http://www.scopus.com/inward/record.url?scp=84947967214&partnerID=8YFLogxK
U2 - 10.1039/c5cc06094j
DO - 10.1039/c5cc06094j
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C2 - 26455447
AN - SCOPUS:84947967214
SN - 1359-7345
VL - 51
SP - 17136
EP - 17139
JO - Chemical Communications
JF - Chemical Communications
IS - 96
ER -