Bioavailability of a pediatric amlodipine suspension

Dorothy A. Lyszkiewicz; Zina Levichek; Eran Kozer; Yaron Yagev; Myla Moretti; Marjie Hard; Gideon Koren

doi:10.1007/s00467-003-1088-2

Bioavailability of a pediatric amlodipine suspension

Dorothy A. Lyszkiewicz
, Zina Levichek
, Eran Kozer
, Yaron Yagev
, Myla Moretti
, Marjie Hard
, Gideon Koren

نتاج البحث: نشر في مجلة › مقالة › مراجعة النظراء

16 اقتباسات (Scopus)

ملخص

Currently, a suspension of crushed tablets of amlodidpine is widely used in children with hypertension without knowledge of its bioavailability. A comparative bioavailability study of a tablet and suspension formulation of amlodipine was completed in 20 healthy adult volunteers. Bioequivalence of the suspension was not different from the tablets. These results support the use of the suspension in children who cannot take the tablet.

اللغة الأصلية	الإنجليزيّة
الصفحات (من إلى)	675-678
عدد الصفحات	4
دورية	Pediatric Nephrology
مستوى الصوت	18
رقم الإصدار	7
المعرِّفات الرقمية للأشياء	https://doi.org/10.1007/s00467-003-1088-2
حالة النشر	نُشِر - 1 يوليو 2003
منشور خارجيًا	نعم

الوصول إلى المستند

10.1007/s00467-003-1088-2

الملفات والروابط الأخرى

Link to publication in Scopus

قم بذكر هذا

@article{fd4a86e837dd4ac0b04fc3f09fee5c21,

title = "Bioavailability of a pediatric amlodipine suspension",

abstract = "Currently, a suspension of crushed tablets of amlodidpine is widely used in children with hypertension without knowledge of its bioavailability. A comparative bioavailability study of a tablet and suspension formulation of amlodipine was completed in 20 healthy adult volunteers. Bioequivalence of the suspension was not different from the tablets. These results support the use of the suspension in children who cannot take the tablet.",

keywords = "Amlodipine, Bioavailability, Bioequivalence, Pediatric formulation, Stability, Suspension",

author = "Lyszkiewicz, \{Dorothy A.\} and Zina Levichek and Eran Kozer and Yaron Yagev and Myla Moretti and Marjie Hard and Gideon Koren",

year = "2003",

month = jul,

day = "1",

doi = "10.1007/s00467-003-1088-2",

language = "אנגלית",

volume = "18",

pages = "675--678",

journal = "Pediatric Nephrology",

issn = "0931-041X",

publisher = "Springer Science and Business Media Deutschland GmbH",

number = "7",

}

TY - JOUR

T1 - Bioavailability of a pediatric amlodipine suspension

AU - Lyszkiewicz, Dorothy A.

AU - Levichek, Zina

AU - Kozer, Eran

AU - Yagev, Yaron

AU - Moretti, Myla

AU - Hard, Marjie

AU - Koren, Gideon

PY - 2003/7/1

Y1 - 2003/7/1

N2 - Currently, a suspension of crushed tablets of amlodidpine is widely used in children with hypertension without knowledge of its bioavailability. A comparative bioavailability study of a tablet and suspension formulation of amlodipine was completed in 20 healthy adult volunteers. Bioequivalence of the suspension was not different from the tablets. These results support the use of the suspension in children who cannot take the tablet.

AB - Currently, a suspension of crushed tablets of amlodidpine is widely used in children with hypertension without knowledge of its bioavailability. A comparative bioavailability study of a tablet and suspension formulation of amlodipine was completed in 20 healthy adult volunteers. Bioequivalence of the suspension was not different from the tablets. These results support the use of the suspension in children who cannot take the tablet.

KW - Amlodipine

KW - Bioavailability

KW - Bioequivalence

KW - Pediatric formulation

KW - Stability

KW - Suspension

UR - https://www.scopus.com/pages/publications/0038353780

U2 - 10.1007/s00467-003-1088-2

DO - 10.1007/s00467-003-1088-2

M3 - ???researchoutput.researchoutputtypes.contributiontojournal.article???

C2 - 12734745

AN - SCOPUS:0038353780

SN - 0931-041X

VL - 18

SP - 675

EP - 678

JO - Pediatric Nephrology

JF - Pediatric Nephrology

IS - 7

ER -

Bioavailability of a pediatric amlodipine suspension

ملخص

الوصول إلى المستند

الملفات والروابط الأخرى

بصمة

قم بذكر هذا