Adult infection with hepatitis A despite declining endemicity; in favor of adult vaccination

David Gillis, Itamar Grotto, Daniel Mimouni, Michael Huerta, Michael Gdalevich, Ofer Shpilberg

نتاج البحث: نشر في مجلةمقالةمراجعة النظراء

5 اقتباسات (Scopus)

ملخص

Seropositivity against hepatitis A was examined among 4806 standing army personnel (4497 males and 309 females) during 1998-1999. Each bi-annual birth cohort examined showed a decline in seropositivity compared to the previous one. When compared with a study performed in 1989, however, for each of the 1961-1962, 1963-1964, 1965-1966, 1967-1968 and 1969-1970 birth cohorts examined, the 1998-1999 study showed 5-15% higher seropositivity. This trend remained after controlling for differences between the two studies in ethnic origin, sibship size and level of education. The overall seroconversion rate is estimated as 1.15% per year and the clinical to subclinical ratio as 1:14. Thus, hepatitis A infection continues to occur in the young adult age group and vaccination of this group should be considered.

اللغة الأصليةالإنجليزيّة
الصفحات (من إلى)2243-2248
عدد الصفحات6
دوريةVaccine
مستوى الصوت20
رقم الإصدار17-18
المعرِّفات الرقمية للأشياء
حالة النشرنُشِر - 22 مايو 2002
منشور خارجيًانعم

بصمة

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