A role for tumor suppressor protein p53 in the fidelity of DNA synthesis and resistance towards nucleoside analogs

Keyphrases

• Excision 100%
• Nucleoside Analogues 100%
• DNA Polymerase 100%
• Tumor Protein p53 (TP53) 100%
• Exonuclease Activity 100%
• Fidelity of DNA Synthesis 100%
• 3′-5′ Exonuclease Activity 100%
• Exonuclease 66%
• Transversion mutations 66%
• Anticancer 33%
• Nuclear Extract 33%
• Recombinant 33%
• DNA Synthesis 33%
• Acquired Resistance 33%
• Biochemical Mechanism 33%
• Whole Cell 33%
• Cellular DNA 33%
• Mutation Spectrum 33%
• Genome Integrity 33%
• Mutator Phenotype 33%
• Proofreading Exonuclease 33%
• Viral DNA Polymerase 33%
• Antiviral nucleoside Analogues 33%
• DNA Replication 33%
• Wild-type p53 33%
• Exonucleolytic Proofreading 33%
• Mispair 33%
• Cytoplasmic Extract 33%
• Proofreading Activity 33%

Biochemistry, Genetics and Molecular Biology

• Nucleoside Analog 100%